HIV swiftly guts the immune system

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Getting to the Guts of HIV Pathogenesis

Two groups have shown that, as in macaques infected with simian immunodeficiency virus (SIV), intestinal CD4(+) T cells are selectively and rapidly depleted in the intestine of HIV-infected patients. Depletion of intestinal CD4(+) T cells occurred at all stages of infection regardless of highly active antiretroviral therapy (HAART). Here we discuss the important implications of these papers for...

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ژورنال

عنوان ژورنال: Nature Medicine

سال: 2005

ISSN: 1078-8956,1546-170X

DOI: 10.1038/nm0505-469